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科生景肽团队文献(部分)

1、Structures of wild-type and H451N mutant human lymphocyte potassium channel KV1.3.

Liu S, Zhao Y, Dong H, Xiao L, Zhang Y, Yang Y, Ong ST, Chandy KG, Zhang L, Tian C.

Cell Discov. 2021 Jun 1;7(1):39. doi: 10.1038/s41421-021-00269-y. PMID: 34059645 Free PMC article.


2、Dipolar coupling-based electron paramagnetic resonance method for protease enzymatic characterization and inhibitor screening.

Yu L, Liu A, Zhang B, Kuang J, Guo X, Tian C, Lu Y.

Chem Commun (Camb). 2021 Sep 21;57(75):9602-9605. doi: 10.1039/d1cc03301h. PMID: 34546243


3、Identification and architecture of a putative secretion tube across mycobacterial outer envelope.

Cai X, Liu L, Qiu C, Wen C, He Y, Cui Y, Li S, Zhang X, Zhang L, Tian C, Bi L, Zhou ZH, Gong W.

Sci Adv. 2021 Aug 20;7(34):eabg5656. doi: 10.1126/sciadv.abg5656. Print 2021 Aug. PMID: 34417177 Free PMC article.


4、Structural basis of human α7 nicotinic acetylcholine receptor activation.

Zhao Y, Liu S, Zhou Y, Zhang M, Chen H, Eric Xu H, Sun D, Liu L, Tian C.

Cell Res. 2021 May 6. doi: 10.1038/s41422-021-00509-6. Online ahead of print. PMID: 33958730


5、Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster.

Zhou X, Gao Y, Wang W, Yang X, Yang X, Liu F, Tang Y, Lam SM, Shui G, Yu L, Tian C, Guddat LW, Wang Q, Rao Z, Gong H.

Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2022308118. doi: 10.1073/pnas.2022308118. PMID: 33876763 Free article.


6、Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan.

Ling S, Shi P, Liu S, Meng X, Zhou Y, Sun W, Chang S, Zhang X, Zhang L, Shi C, Sun D, Liu L, Tian C.

Cell Res. 2021 Apr;31(4):383-394. doi: 10.1038/s41422-021-00474-0. Epub 2021 Feb 18. PMID: 33603117


7、Secondary structure and transmembrane topology analysis of the N-terminal domain of the inner membrane protein EccE1 from M. smegmatis using site-directed spin labeling EPR.

Yu L, Fang W, He Y, Cai W, Wei W, Tian C.

Biochim Biophys Acta Biomembr. 2021 Feb 1;1863(2):183515. doi: 10.1016/j.bbamem.2020.183515. Epub 2020 Nov 24. PMID: 33245893


8、Chemical synthesis of di-ubiquitin modified histones for further biochemical studies.

Li JB, Liang J, Tian C.

Methods Enzymol. 2020;639:263-287. doi: 10.1016/bs.mie.2020.04.059. Epub 2020 May 10. PMID: 32475405


9、Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.

Sun D, Liu S, Li S, Zhang M, Yang F, Wen M, Shi P, Wang T, Pan M, Chang S, Zhang X, Zhang L, Tian C, Liu L.

Elife. 2020 Sep 11;9:e57096. doi: 10.7554/eLife.57096. PMID: 32915133 Free PMC article.


10、Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis.

Li S, Yang F, Sun D, Zhang Y, Zhang M, Liu S, Zhou P, Shi C, Zhang L, Tian C.

Cell Res. 2020 Nov;30(11):1049-1052. doi: 10.1038/s41422-020-00407-3. Epub 2020 Sep 8.

PMID: 32901112 Free PMC article. No abstract available.


11、Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF.

Gong H, Gao Y, Zhou X, Xiao Y, Wang W, Tang Y, Zhou S, Zhang Y, Ji W, Yu L, Tian C, Lam SM, Shui G, Guddat LW, Wong LL, Wang Q, Rao Z.

Nat Commun. 2020 Aug 25;11(1):4245. doi: 10.1038/s41467-020-18011-9. PMID: 32843629 Free PMC article.


12、Single-particle cryo-EM structural studies of the β2AR-Gs complex bound with a full agonist formoterol.

Zhang Y, Yang F, Ling S, Lv P, Zhou Y, Fang W, Sun W, Zhang L, Shi P, Tian C.

Cell Discov. 2020 Jul 7;6:45. doi: 10.1038/s41421-020-0176-9. eCollection 2020. PMID: 32655881 Free PMC article. No abstract available.


13、A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET.

Shi P , Zhang Y , Lv P , Fang W , Ling S , Guo X , Li D , Liu S , Sun D , Zhang L , Liu D , Zheng JS , Tian C .

Chem Commun (Camb). 2020 Jun 25;56(51):6941-6944. doi: 10.1039/d0cc02691c. PMID: 32435777


14、Synthesis of Disulfide Surrogate Peptides Incorporating Large-Span Surrogate Bridges Through a Native-Chemical-Ligation-Assisted Diaminodiacid Strategy.

Qu Q, Gao S, Wu F, Zhang MG, Li Y, Zhang LH, Bierer D, Tian CL, Zheng JS, Liu L.

Angew Chem Int Ed Engl. 2020 Apr 6;59(15):6037-6045. doi: 10.1002/anie.201915358. Epub 2020 Mar 17. PMID: 32060988


15、The New Salicylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis.

Huang DL, Li Y, Liang J, Yu L, Xue M, Cao XX, Xiao B, Tian CL, Liu L, Zheng JS.

J Am Chem Soc. 2020 May 13;142(19):8790-8799. doi: 10.1021/jacs.0c01561. Epub 2020 Apr 30. PMID: 32286828


16、Chemical Synthesis of Native S-Palmitoylated Membrane Proteins through Removable-Backbone-Modification-Assisted Ser/Thr Ligation.

Huang DL, Montigny C, Zheng Y, Beswick V, Li Y, Cao XX, Barbot T, Jaxel C, Liang J, Xue M, Tian CL, Jamin N, Zheng JS.

Angew Chem Int Ed Engl. 2020 Mar 23;59(13):5178-5184. doi: 10.1002/anie.201914836. Epub 2020 Feb 12. PMID: 31846559


17、Ion channel modulation by scorpion hemolymph and its defensin ingredients highlights origin of neurotoxins in telson formed in Paleozoic scorpions.

Meng L, Zhao Y, Qu D, Xie Z, Guo X, Zhu Z, Chen Z, Zhang L, Li W, Cao Z, Tian C, Wu Y.

Int J Biol Macromol. 2020 Apr 1;148:351-363. doi: 10.1016/j.ijbiomac.2020.01.133. Epub 2020 Jan 15. PMID: 31954123


18、Chemical synthesis of proteins using peptide hydrazides as thioester surrogates

Ji-Shen Zheng 1, Shan Tang, Yun-Kun Qi, Zhi-Peng Wang, Lei Liu

Nat Protoc. 2013 Dec;8(12):2483-95. doi: 10.1038/nprot.2013.152. Epub 2013 Nov 14.


19、Chemical synthesis of membrane proteins by the removable backbone modification method.

Tang S, et al. Nat Protoc. 2017. PMID: 29189771