科生景肽 专利/文献
KS-V Peptide
专利文献 PATENT LITERATURE
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Chemical synthesis of membrane proteins by the removable backbone modification method.
○ 2017.03 Chemical synthesis of membrane proteins by the removable backbone modification method.
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Chemical synthesis of proteins using peptide hydrazides as thioester surrogates
○ 2013.12 Chemical synthesis of proteins using peptide hydrazides as thioester surrogates
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Ion channel modulation by scorpion hemolymph and its defensin ingredients highlights origin of neurotoxins in telson formed in Paleozoic scorpions.
○ 2020.01 Ion channel modulation by scorpion hemolymph and its defensin ingredients highlights origin of neurotoxins in telson formed in Paleozoic scorpions.
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Chemical Synthesis of Native S-Palmitoylated Membrane Proteins through Removable-Backbone-Modification-Assisted Ser/Thr Ligation.
○ 2020.02 Chemical Synthesis of Native S-Palmitoylated Membrane Proteins through Removable-Backbone-Modification-Assisted Ser/Thr Ligation.
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The New Salicylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis.
○ 2020.04 The New Salicylaldehyde S,S-Propanedithioacetal Ester Enables N-to-C Sequential Native Chemical Ligation and Ser/Thr Ligation for Chemical Protein Synthesis.
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Synthesis of Disulfide Surrogate Peptides Incorporating Large-Span Surrogate Bridges Through a Native-Chemical-Ligation-Assisted Diaminodiacid Strategy.
○ 2020.03 Synthesis of Disulfide Surrogate Peptides Incorporating Large-Span Surrogate Bridges Through a Native-Chemical-Ligation-Assisted Diaminodiacid Strategy.
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A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET.
○ 2020.06 A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET.
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Single-particle cryo-EM structural studies of the β2AR-Gs complex bound with a full agonist formoterol.
○ 2020.07 Single-particle cryo-EM structural studies of the β2AR-Gs complex bound with a full agonist formoterol.
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Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF.
○ 2020.08 Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF.
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Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis.
○ 2020.09 Cryo-EM structure of the hyperpolarization-activated inwardly rectifying potassium channel KAT1 from Arabidopsis.
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Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.
○ 2020.09 Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1.
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Chemical synthesis of di-ubiquitin modified histones for further biochemical studies.
○ 2020.05 Chemical synthesis of di-ubiquitin modified histones for further biochemical studies.
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Secondary structure and transmembrane topology analysis of the N-terminal domain of the inner membrane protein EccE1 from M. smegmatis using site-directed spin labeling EPR.
○ 2020.11 Secondary structure and transmembrane topology analysis of the N-terminal domain of the inner membrane protein EccE1 from M. smegmatis using site-directed spin labeling EPR.
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Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan.
○ 2021.02 Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan.
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Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster.
○ 2021.04 Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster.
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Structural basis of human α7 nicotinic acetylcholine receptor activation.
○ 2021.05 Structural basis of human α7 nicotinic acetylcholine receptor activation.
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Identification and architecture of a putative secretion tube across mycobacterial outer envelope.
○ 2021.08 Identification and architecture of a putative secretion tube across mycobacterial outer envelope.
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Dipolar coupling-based electron paramagnetic resonance method for protease enzymatic characterization and inhibitor screening.
○ 2021.09 Dipolar coupling-based electron paramagnetic resonance method for protease enzymatic characterization and inhibitor screening.
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Structures of wild-type and H451N mutant human lymphocyte potassium channel KV1.3.
○ 2021.06 Structures of wild-type and H451N mutant human lymphocyte potassium channel KV1.3.
合肥科生景肽生物科技有限公司
地址：安徽省合肥市高新区望江西路5089号中
科大先研院智源楼
电话：0551-65120828 0551-65120826
邮箱：sales@difficultpeptide.com
合肥科生景肽生物科技有限公司
地址：安徽省合肥市高新区望江西路5089号中
科大先研院智源楼
电话：0551-65120828 0551-65120826
邮箱：sales@difficultpeptide.com
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